Brain abscess caused by Cladophialophora Bantiana in an immunocompetent host: need for a novel cost-effective antifungal agent.
نویسندگان
چکیده
We report a 53-year-old male who presented with headache, tremor and memory disturbance. Radiological evaluation was suggestive of brain abscess. He underwent gross total excision of the cerebral abscess. The histopathological examination and pus culture was suggestive of brain abscess caused by Cladophialophora bantiana. Authors report a rare case of biopsy and culture proven Cladophialophora bantiana brain abscess in an immunocompetent host. The authors review the relevant literature and current treatment options while emphasizing the need for a cost-effective novel antifungal drug to salvage a subset of patients suffering from this rare but increasingly frequent condition.
منابع مشابه
Fatal cerebral abscess caused by Cladophialophora bantiana.
Primary cerebral phaeohyphomycosis is caused by pigmented fungi that exhibit distinct neurotropism often in immunocompetent individuals. A 20-yr-old male presented with multiple brain abscess which was subsequently proven microbiologically to be due to Cladophialophora Bantiana. In spite of near total excision and appropriate antifungal agents succumbed to his illness. We report this case to hi...
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Phaeohyphomycosis is a term used to describe infections caused by dematiaceous fungi, i.e. fungi which contain melanin in their cell wall. Cladophialophora bantiana has been implicated to cause brain abscess in immunocompromised patients. Infection caused by Cladophialophora bantiana in an immunocompetent host is relatively rare. Surgical site infection at abdominal subcutaneous tissue caused b...
متن کاملCladophialophora bantiana: a rare cause of fungal brain abscess. Clinical aspects and new therapeutic options.
Black molds or dematiaceous fungi are rare etiologic agents of intracerebral abscesses and such infections carry a high mortality of up to 70% despite combined surgical and antifungal therapy. While the growing use of immunosuppressive therapies and organ transplantation have caused an increase in the incidence of rare fungal cerebral infections, occurrence in immunocompetent hosts is also poss...
متن کاملA 35-year-old woman with prior renal transplantation admitted with a temporal brain abscess.
Diagnosis: Cladophialophora bantiana brain abscess. Cladophialophora are dematiaceous molds typically found in soil and decaying plants [1]. The various Cladophialophora species are responsible for a diversity of disease states, including brain abscesses (C. bantiana), chromoblastomycosis, and other skin infections (C. carionii and C. boppii) [2]. C. bantiana is the most common fungus to cause ...
متن کاملPhaeohyphomycosis caused by Cladophialophora bantiana.
BACKGROUND Cladophialophora bantiana is the most frequent cause of central nervous system phaeohyphomycosis. AIMS We report a case of phaeohyphomycosis by C. bantiana in a patient with underlying lung disease on steroid therapy. METHODS An 81-year-old male was admitted in August 2011 with a history of difficulty speaking and deflection of the oral commeasure to the left side with a brain ab...
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ورودعنوان ژورنال:
- Indian journal of medical microbiology
دوره 26 3 شماره
صفحات -
تاریخ انتشار 2008